I was just listening to this Masterclass about sleep and they mentioned a study done with vaccinations that found when people get flu vaccines when they are not getting proper sleep, the vaccine elicited about half the immune response that it did in people who were getting healthy amounts of sleep. He recommended that whenever you get vaccinated for anything that you be careful to get really good night’s sleep every night for the week before and after you get the shot. I haven’t heard anyone else talking about this but it seems like an easy step we can take to increase the effectiveness and likely reduce the side effects of the vaccine.
https://www.masterclass.com/classes/matthew-walker-teaches-the-science-of-better-sleep